{"id":2260,"date":"2024-02-18T11:53:11","date_gmt":"2024-02-18T03:53:11","guid":{"rendered":"https:\/\/unionmedin.com\/?p=2260"},"modified":"2024-02-18T11:53:11","modified_gmt":"2024-02-18T03:53:11","slug":"2023%e5%8c%bb%e4%bf%9d%e5%9b%bd%e8%b0%88%e5%b7%b2%e5%bc%80%e5%a7%8b%ef%bc%8c%e4%b8%ba%e6%9c%9f%e5%9b%9b%e5%a4%a9%ef%bc%8c12%e6%9c%88%e5%88%9d%e6%88%96%e5%b0%86%e5%85%ac%e5%b8%83%e7%bb%93%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/unionmedin.com\/?p=2260","title":{"rendered":"2023\u533b\u4fdd\u56fd\u8c08\u5df2\u5f00\u59cb\uff0c\u4e3a\u671f\u56db\u5929\uff0c12\u6708\u521d\u6216\u5c06\u516c\u5e03\u7ed3\u679c"},"content":{"rendered":"<div class=\"detail\">\n<p>\u636e\u8d22\u8054\u793e\u62a5\u9053\uff0c\u7b2c\u4e00\u8d22\u7ecf\u3001\u84dd\u9cb8\u8bb0\u8005\u7b49\u591a\u65b9\u4fe1\u606f\uff0c2023\u5e74\u56fd\u5bb6\u533b\u4fdd\u8c08\u5224\u4e8e11\u670817\u65e5\uff09\u5728\u5317\u4eac\u5168\u56fd\u603b\u5de5\u4f1a\u56fd\u9645\u4ea4\u6d41\u4e2d\u5fc3\u4e3e\u884c\uff0c\u603b\u5171\u4e3a\u671f\u56db\u5929\u3002<\/p>\n<\/p>\n<p>\u6b64\u5916\uff0c\u636e\u7b2c\u4e00\u8d22\u7ecf\u8bb0\u8005\u4e86\u89e3\u6d88\u606f\uff0c\u90e8\u5206\u56fd\u4ea7PD-1\u6297\u764c\u836f\u65b0\u589e\u9002\u5e94\u8bc1\u6216\u8005\u534f\u8bae\u5230\u671f\u7eed\u7ea6\u8c08\u5224\u5c06\u4f1a\u5728\u5468\u65e5\uff0811\u670819\u65e5\uff09\u8fdb\u884c\u3002<\/p>\n<\/p>\n<p>\u53c2\u52a0\u5b8c\u8c08\u5224\u7684\u836f\u4f01\u4ee3\u8868\u5904\u5f97\u77e5\uff0c\u624b\u673a\u3001\u8ba1\u7b97\u5668\u7b49\u8bbe\u5907\u5747\u4e0d\u88ab\u5141\u8bb8\u5e26\u5165\u4f1a\u573a\uff0c\u9700\u8981\u9501\u5728\u4f1a\u8bae\u5ba4\u5916\u7684\u67dc\u5b50\u4e2d\u3002<\/p>\n<\/p>\n<p>\u636e\u56fd\u5bb6\u533b\u4fdd\u5c40\u516c\u544a\uff0c\u4eca\u5e74\u5171\u6709390\u4e2a\u836f\u54c1\u901a\u8fc7\u521d\u6b65\u5f62\u5f0f\u5ba1\u67e5\uff0c\u901a\u8fc7\u6b63\u5f0f\u5f62\u5f0f\u5ba1\u67e5\u7684\u6709386\u4e2a\uff0c\u800c\u6700\u7ec8\u8fdb\u5165\u8c08\u5224\/\u7ade\u4ef7\u73af\u8282\u7684\u4ec5168\u4e2a\u836f\u54c1\u3002\u6700\u7ec8\u7ed3\u679c\u6709\u671b\u4e8e12\u6708\u5de6\u53f3\u516c\u5e03\u3002<\/p>\n<\/p>\n<p>\u636e\u5929\u98ce\u8bc1\u5238\u6309\u9776\u70b9\u68b3\u7406\uff0c PD-1\u7c7b\uff0c \u672c\u6b21\u8c08\u5224\u672a\u6709\u76ee\u5f55\u5916\u8fdb\u53e3\/\u56fd\u4ea7PD-1\u901a\u8fc7\u5f62\u5f0f\u5ba1\u67e5\uff0c \u56fd\u4ea7\u836f\u54c1\u6709\u76ee\u5f55\u5185\u4fe1\u8fea\u5229\u5355\u6297\uff0c \u5361\u745e\u5229\u73e0\u5355\u6297\uff0c \u7279\u745e\u666e\u5229\u5355\u6297\u3001 \u66ff\u96f7\u5229\u73e0\u5355\u6297\u3002\u5176\u4e2d\u7279\u745e\u666e\u5229\u5355\u6297\u3001\u5361\u745e\u5229\u73e0\u5355\u6297\u4ee5\u53ca\u66ff\u96f7\u5229\u73e0\u5355\u6297\u5747\u6709\u65b0\u589e\u9002\u5e94\u75c7\u3002<\/p>\n<\/p>\n<p>BTKi\u7c7b\uff0c \u76ee\u524d\u5df2\u4e0a\u5e02\u7684BTKi\u4e3b\u8981\u5305\u62ec\uff1a\u827e\u4f2f\u7ef4\/\u5f3a\u751f\u7684\u4f0a\u5e03\u66ff\u5c3c\uff0c \u767e\u6d4e\u795e\u5dde\u7684\u6cfd\u5e03\u66ff\u5c3c\u548c\u8bfa\u8bda\u5065\u534e\u7684\u5965\u5e03\u66ff\u5c3c\u3002\u6cfd\u5e03\u66ff\u5c3c\u548c\u5965\u5e03\u66ff\u5c3c\u5747\u53c2\u4e0e\u672c\u8f6e\u533b\u4fdd\u8c08\u5224\u3002EGFR-TKi\u7c7b\uff0c\u76ee\u524d\u5df2\u4e0a\u5e02\u7684EGFR-TKi\u4e3b\u8981\u5305\u62ec\uff1a\u8d1d\u8fbe\u7684\u57c3\u514b\u66ff\u5c3c\u3001 \u8d1d\u798f\u66ff\u5c3c\uff0c \u827e\u529b\u65af\u7684\u4f0f\u7f8e\u66ff\u5c3c\uff0c \u6c5f\u82cf\u8c6a\u68ee\u7684\u963f\u7f8e\u66ff\u5c3c\uff0c \u963f\u65af\u5229\u5eb7\u7684\u5409\u975e\u66ff\u5c3c\u3001\u5965\u5e0c\u66ff\u5c3c\u3002\u9700\u91cd\u70b9\u5173\u6ce8\u5965\u5e0c\u66ff\u5c3c\u672f\u540e\u8f85\u52a9\u9002\u5e94\u75c7\u7684\u533b\u4fdd\u8c08\u5224\u7ed3\u679c\u3002<\/p>\n<\/p>\n<p>\u53e6\u636e\u521d\u5ba1\u540d\u5355\uff0cCAR-T \u7597\u6cd5\u963f\u57fa\u4ed1\u8d5b\u3001\u745e\u57fa\u5965\u4ed1\u8d5b\u4e5f\u5c06\u518d\u6b21\u52a0\u5165\u4eca\u5e74\u7684\u8c08\u5224\u4e4b\u5217\uff1bADC\u65b9\u9762\uff0c\u9664\u53bb\u5e74\u65b0\u8fdb\u533b\u4fdd\u7684\u7f57\u6c0f\u6069\u7f8e\u66f2\u59a5\u73e0\u5355\u6297\u4ee5\u53ca Seagen\/\u6b66\u7530\u7684\u7ef4\u5e03\u59a5\u6614\u5355\u6297\u5916\uff0c\u76ee\u5f55\u5916\u7684\u6709\u8f89\u745e\u5965\u52a0\u4f0a\u59a5\u73e0\u5355\u6297\u3001\u7f57\u6c0f\u7ef4\u6cca\u59a5\u73e0\u5355\u6297\u3001\u5409\u5229\u5fb3\u6208\u6c99\u59a5\u73e0\u5355\u6297\u4ee5\u53ca\u7b2c\u4e00\u4e09\u5171\/\u963f\u65af\u5229\u5eb7\u5fb7\u66f2\u59a5\u73e0\u5355\u6297\u3002<\/p>\n<\/p>\n<p>\u4ece\u8c03\u6574\u89c4\u5219\u6765\u770b\uff0c\u5929\u98ce\u8bc1\u5238\u8ba4\u4e3a\uff0c\u836f\u54c1\u5728\u591a\u4e2a\u9636\u6bb5\u7684\u964d\u5e45\u90fd\u5c06\u4f1a\u66f4\u5c0f\uff0c\u9884\u8ba1\u672c\u6b21\u7eed\u7ea6\u89c4\u5219\u7684\u8c03\u6574\u4ece\u591a\u4e2a\u65b9\u9762\u4f7f\u5f97\u964d\u5e45\u66f4\u52a0\u5408\u7406\u6e29\u548c\u3002<\/p>\n<\/p>\n<p>\u636e\u6089\uff0c\u4eca\u5e74\u5171\u6709168\u4e2a\u836f\u54c1\u8fdb\u5165\u8c08\u5224\u7ade\u4ef7\u73af\u8282\uff0c\u4e3a\u5386\u5e74\u6765\u54c1\u79cd\u6700\u591a\u7684\u4e00\u6b21\uff0c\u4f46\u5bf9\u4e8e\u4eca\u5e74\u53c2\u4e0e\u8c08\u5224\u836f\u54c1\u7684\u964d\u4ef7\u5e45\u5ea6\uff0c\u6709\u5206\u6790\u9884\u6d4b\uff0c\u5728\u7eed\u7ea6\u65b0\u89c4\u5219\u4e0b\u5404\u5bb6\u964d\u4ef7\u5e45\u5ea6\u5c06\u5c0f\u4e8e\u9884\u671f\uff0c\u540e\u7eed\u5c06\u4fc3\u8fdb\u836f\u54c1\u8fbe\u6210\u66f4\u9ad8\u7684\u722c\u5761\u4ee5\u53ca\u5cf0\u503c\u9500\u552e\u3002<\/p>\n<\/p>\n<p>\u5728\u53bb\u5e74\u7684\u533b\u4fdd\u76ee\u5f55\u8c03\u6574\u4e2d \uff0c\u5171198\u4e2a\u76ee\u5f55\u5916\u836f\u54c1\u901a\u8fc7\u5f62\u5f0f\u5ba1\u67e5\uff0c\u6700\u7ec8111\u4e2a\u6210\u529f\u51c6\u5165\uff0c\u6210\u529f\u7387\u7ea6\u4e3a56%\uff1b\u76ee\u5f55\u5916\u72ec\u5bb6\u836f\u54c1\u4e2d\uff0c157\u4e2a\u901a\u8fc7\u5f62\u5f0f\u5ba1\u67e5\uff0c91\u4e2a\u6210\u529f\u51c6\u5165\uff0c\u603b\u4f53\u6210\u529f\u738758%\u3002<\/p>\n<\/p>\n<p>\u6b64\u5916\uff0c9\u6708\uff0c\u56fd\u5bb6\u533b\u4fdd\u5c40\u65b9\u9762\u66fe\u5728\u65b0\u95fb\u53d1\u5e03\u4f1a\u4e0a\u8868\u793a\uff0c\u9884\u8ba112\u6708\u521d\u516c\u5e03\u76ee\u5f55\u8c03\u6574\u7ed3\u679c\uff0c\u8ba1\u5212\u4ece2024\u5e741\u67081\u65e5\u8d77\u6b63\u5f0f\u6267\u884c\u65b0\u7248\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\u3002<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>[db:\u6458\u8981]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[5],"tags":[33],"_links":{"self":[{"href":"https:\/\/unionmedin.com\/index.php?rest_route=\/wp\/v2\/posts\/2260"}],"collection":[{"href":"https:\/\/unionmedin.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/unionmedin.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/unionmedin.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/unionmedin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2260"}],"version-history":[{"count":0,"href":"https:\/\/unionmedin.com\/index.php?rest_route=\/wp\/v2\/posts\/2260\/revisions"}],"wp:attachment":[{"href":"https:\/\/unionmedin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2260"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/unionmedin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2260"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/unionmedin.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2260"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}